KARYA ILMIAH

Pengarang
Weny J.A. Musa
Subjek
- Sains
Abstrak
Two triterpenoid compounds, 3?-hydroxy-Olean-12-en- 28-oic acid (1) and 3,19-Dihydroxyurs-12-en-28-oic acid (2) were isolated from the leaves of Saurauia vulcani Korth. (Actinidiaceae). The chemical structures of compounds 1–2 were elucidated with spectroscopic data (UV, IR, 1H, 13C, DEPT 135º, HMQC, HMBC, 1H-1H COSY NMR) and MS as well as compared with previously reported spectra data. All the compounds were evaluated for their anti-cholesterol activity by the Liebermann-Burchard (LB) colorimetric assay. Compound 1–2 showed a remarkable anti-cholesterol activity. Most importantly, the raised concentration of 1–2 exhibited a dose-dependent manner. The discoveries of anti-cholesterol compounds 1–2 were first reported.
Penerbit
Marcel Dekker Inc
Kontributor
-
Terbit
2019
Tipe Material
ARTIKEL
Identifier
-
Right
-
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