Penulis / NIM
SINTIA FRILIANTI GUMALANGIT / 821414088
Program Studi
S1 - FARMASI
Pembimbing 1 / NIDN
MOHAMMAD ADAM MUSTAPA, S.Si., M.Sc / 0022047702
Pembimbing 2 / NIDN
SYAM S KUMAJI, S.Pd., M.Kes / 0013038204
Abstrak
ABSTRAK
Sintia Frilianti Gumalangit, 2018. Perbandingan Ekstrak Daun Binahong Hijau dan Daun Binahong Merah (Anredera cordifolia (Ten) Steenis) Dalam Menghambat Pertumbuhan Bakteri Shigella sp dan Bacillus subtilis. Skripsi, Program Studi S1 Farmasi, Jurusan Farmasi, Fakultas Olahraga dan Kesehatan, Universitas Negeri Gorontalo, Pembimbing I Mohammad Adam Mustapa, S.Si., M.Sc. dan Pembimbing II Syam Kumaji, S.Pd., M.Kes.
Binahong merupakan suatu tanaman yang mengandung senyawa flavonoid yang berfungsi sebagai antibakteri terhadap bakteri Shigella sp dan Bacillus subtilis. Tujuan penelitian ini Untuk mengetahui perbandingan ekstrak daun binahong hijau dan daun binahong merah (Anredera cordifolia (Ten.) Steenis) dalam menghambat pertumbuhan bakteri Shigella sp dan Bacillus subtilis dan untuk mengetahui perbedaan yang signifikan antara ekstrak daun binahong hijau dan daun binahong merah terhadap efektivitas dalam menghambat pertumbuhan bakteri shigella sp dan bakteri Bacillus subtilis. Metode menggunakan yaitu eksperimental laboratorium. Hasil penelitian yang diperoleh pada ekstrak daun binahong hijau pada bakteri Shigella sp konsentrasi 25% diperoleh hasil 13,67 mm, konsentras 50% dengan hasil 17 mm, dan konsentrasi 75% diperoleh hasil 19 mm. Sedangkan pada bakteri Bacillus subtilisis konsentrasi 25% diperoleh 10,67 mm, konsentrasi 50% dengan hasil 17 mm, dan konsentrasi 75% diperoleh hasil 19,33 mm. Pada ekstrak daun binahong merah pada bakteri Shigella sp konsentrasi 25% diperoleh hasil 14,33 mm, konsentras 50% dengan hasil 18,33 mm, dan konsentrasi 75% diperoleh hasil 21,33 mm. Sedangkan pada bakteri Bacillus subtilisis konsentrasi 25% diperoleh 12 mm, konsentrasi 50% dengan hasil 14,67 mm, dan konsentrasi 75% diperoleh hasil 16,67 mm.
Kata kunci : Daun Binahong (Anredera cordifolia (Ten) Steenis), Shigella sp, Bacilillus subtilis
ABSTRACT
Sintia Frilianti Gumalangit. 2018. Extract Comparison of Green Madeira-vine Leaves and Red Madeira-vine Leaves (Anredera cordifolia (Ten) Steenis) in Inhibiting The Growth of Bacteria Shigella sp and BacteriaBacillus subtilis. Undergraduate Thesis. Bachelor Study Program. Pharmaceutical Department, Faculty of Sports and Health, Gorontalo State University. Advisor Mohammad Adam Mustapa, S.Si., M.Sc. and co-Advisor Syam Kumaji, S.Pd., M.Kes.
Madeira-vine (Anredera cordifolia (Ten) Steenis) is a plant that contains flavonoids compound serving as antibacterial against bacteria Shigella sp dan Bacillus subtilis. This research aims to determine the extract comparison of green madeira-vine leaves and red madeira-vine leaves (Anredera cordifolia (Ten) Steenis) in inhibiting the growth of bacteria Shigella sp and bacteria Bacillus subtilis and also to determine the significant differences of its effectiveness between the extract of green madeira-vine leaves and the red madeira-vine leaves in inhibiting the growth of bacteria shigella sp and bacteria Bacillus subtilis. The method used in this research is laboratory experimental. The results of the green madeira-vine leaves extract against bacteria Shigella sp are at concentration of 25% is obtained 13,66 mm, at concentration of 50% is 17 mm, and at concentration of 75% is 19 mm. While the results of the green leaves extract against bacteria Bacillus subtilisis are at concentration of 25% is obtained 10,66 mm, at concentration of 50% is 17 mm, and at concentration of 75% is 19,33 mm. In other side, the results of red madeira-vine leaves extract against bacteria Shigella sp are at concentration of 25% is obtained 14,33 mm, at concentration of 50% is 18,33 mm, and at concentration of 75% is 21,33 mm. While the results of the red extract leaves against bacteria Bacillus subtilisis are at concentration of 25% is obtained 12 mm, at concentration of 50% is 14,66 mm, and at concentration of 75% is 16,66 mm.
Keywords: Madeira-vine (Anredera cordifolia (Ten) Steenis) Leaves, Shigella sp, Bacilillus subtilis
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