SCIENTIFIC WORK

Author
Weny J.A. Musa
Subject
- Sains
Abstract
Two triterpenoid compounds, 3?-hydroxy-Olean-12-en- 28-oic acid (1) and 3,19-Dihydroxyurs-12-en-28-oic acid (2) were isolated from the leaves of Saurauia vulcani Korth. (Actinidiaceae). The chemical structures of compounds 1–2 were elucidated with spectroscopic data (UV, IR, 1H, 13C, DEPT 135º, HMQC, HMBC, 1H-1H COSY NMR) and MS as well as compared with previously reported spectra data. All the compounds were evaluated for their anti-cholesterol activity by the Liebermann-Burchard (LB) colorimetric assay. Compound 1–2 showed a remarkable anti-cholesterol activity. Most importantly, the raised concentration of 1–2 exhibited a dose-dependent manner. The discoveries of anti-cholesterol compounds 1–2 were first reported.
Publisher
Marcel Dekker Inc
Contributor
-
Publish
2019
Material Type
ARTIKEL
Right
-
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